Description

2,5-Dimethyl-1-[4-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbaldehyde is a high-purity, functionalized pyrrole derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a pyrrole core with a trifluoromethylphenyl group and an aldehyde functionality, making it a versatile precursor for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs), conductive polymers, and advanced dyes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Catalyst Ligand Development: The pyrrole-aldehyde structure can be modified to create novel ligands for transition metal catalysis in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	2,5-Dimethyl-1-[4-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbaldehyde
CAS No.	256529-25-6
Molecular Formula	C14H12F3NO
Molecular Weight	267.25 g/mol
Synonyms	1H-Pyrrole-3-carboxaldehyde, 2,5-dimethyl-1-[4-(trifluoromethyl)phenyl]-; 2,5-Dimethyl-1-(4-trifluoromethylphenyl)-1H-pyrrole-3-carbaldehyde; 3-Formyl-2,5-dimethyl-1-(4-trifluoromethylphenyl)pyrrole; 256529-25-6; 1-(4-Trifluoromethylphenyl)-2,5-dimethylpyrrole-3-carboxaldehyde; 2,5-Dimethyl-1-(α,α,α-trifluoro-p-tolyl)-1H-pyrrole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemicals and pharmaceutical intermediates. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.