Description

(S)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is a high-value chiral epoxide building block characterized by its trifluoromethylphenoxy moiety. This compound is critical for introducing chirality and fluorinated aromatic functionality into advanced molecular architectures, enhancing properties like metabolic stability and lipophilicity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent for creating specialty polymers with unique thermal and chemical resistance profiles.
• Asymmetric Catalysis Research: A valuable substrate in academic and industrial laboratories for developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value fluorinated compounds for various specialty chemical applications.

Basic Information

Product Name	(S)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane
CAS No.	256372-58-4
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	(S)-(-)-4-(Trifluoromethyl)phenyl glycidyl ether; (S)-1-((4-(Trifluoromethyl)phenoxy)methyl)oxirane; (S)-2-[(4-Trifluoromethylphenoxy)methyl]oxirane; (S)-α-[(4-Trifluoromethylphenoxy)methyl]oxirane; (S)-Glycidyl 4-(trifluoromethyl)phenyl ether; (S)-TFMPGE; (S)-Trifluoromethylphenyl glycidyl ether; (S)-Epichlorohydrin derivative of 4-(Trifluoromethyl)phenol
EINECS	Contact for details

Quality Control

Our production of (S)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. All materials are characterized by advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.480 - 1.490
Density (20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.