Description

2-Bromo-4'-(Trifluoromethyl)Biphenyl is a high-purity, halogenated biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl functional groups, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a core structure for synthesizing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing characteristics.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Bromo-4'-(Trifluoromethyl)Biphenyl
CAS No.	255837-15-1
Molecular Formula	C13H8BrF3
Molecular Weight	301.11 g/mol
Synonyms	2-Bromo-4'-(trifluoromethyl)-1,1'-biphenyl; [1,1'-Biphenyl]-2-bromo-4'-(trifluoromethyl); 4'-(Trifluoromethyl)-2-bromobiphenyl; 2-Bromo-4'-trifluoromethylbiphenyl; 2-Bromo-4'-(trifluoromethyl)diphenyl; 2-Bromobiphenyl-4'-trifluoromethyl
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-(Trifluoromethyl)Biphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.