Description

Boronic Acid, [4-(1,3-Dioxan-2-Yl)Phenyl]- (9Ci) is a specialized aromatic boronic acid derivative featuring a protected aldehyde functionality in the form of a 1,3-dioxane ring. This compound is a high-value synthetic intermediate prized for its role in modern cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific biphenyl or functionalized aromatic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop molecular probes and sensors that leverage boronic acid's affinity for diols, useful in diagnostic applications.
• Academic & Contract Research: Essential for methodological development in organic chemistry laboratories and for custom synthesis projects in CROs/CMOs.

Basic Information

Product Name	Boronic Acid, [4-(1,3-Dioxan-2-Yl)Phenyl]- (9Ci)
CAS No.	254454-02-9
Molecular Formula	C12H15BO4
Molecular Weight	234.06 g/mol
Synonyms	[4-(1,3-Dioxan-2-yl)phenyl]boronic acid; 2-[4-(Borono)phenyl]-1,3-dioxane; 4-(1,3-Dioxan-2-yl)benzeneboronic acid; 4-(1,3-Dioxan-2-yl)phenylboronic acid; (4-(1,3-Dioxan-2-yl)phenyl)boronic acid; Boronic acid, B-[4-(1,3-dioxan-2-yl)phenyl]-; 254454-02-9; 4-(2,2-Dimethyl-1,3-dioxolan-4-yl)phenylboronic acid (related protected form)
EINECS	Contact for details

Quality Control

Our Boronic Acid, [4-(1,3-Dioxan-2-Yl)Phenyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.