Description

3-Pyridinecarboxaldehyde, 5-Ethynyl- (9Ci) is a specialized heterocyclic aldehyde building block featuring a reactive ethynyl substituent. This compound is valued for its dual functionality, serving as a key intermediate in the synthesis of complex molecules for pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized polymers, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in click chemistry applications via its alkyne group for labeling and studying biological systems.
• Ligand Synthesis: Used to prepare novel pyridine-based ligands for transition metal catalysis.
• Academic & Industrial R&D: A versatile reagent for exploratory organic synthesis and method development in research laboratories.

Basic Information

Product Name	3-Pyridinecarboxaldehyde, 5-Ethynyl- (9Ci)
CAS No.	252989-57-4
Molecular Formula	C8H5NO
Molecular Weight	131.13 g/mol
Synonyms	5-Ethynylnicotinaldehyde; 5-Ethynyl-3-pyridinecarboxaldehyde; 5-Ethynylpyridine-3-carbaldehyde; 3-Formyl-5-ethynylpyridine; 5-Ethynyl-3-formylpyridine; 5-Ethynylnicotinaldehyde; Nicotinaldehyde, 5-ethynyl-
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxaldehyde, 5-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flames. Due to its sensitivity, minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.