Description

Benzeneacetic Acid, A-Amino-2-Hydroxy-, Methyl Ester is a specialized chiral amino acid derivative with significant synthetic utility. This compound serves as a crucial pharmaceutical intermediate and building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel APIs, particularly in antibiotic and neurological drug research.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Asymmetric Synthesis: Serves as a precursor or chiral auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Bioconjugation: Functional handle for the modification of biomolecules, proteins, or peptides in drug delivery systems.
• Chemical Biology Research: Tool compound for studying enzyme mechanisms or as a probe in biochemical assays.
• Fine Chemical Production: Building block for the manufacture of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	Benzeneacetic Acid, A-Amino-2-Hydroxy-, Methyl Ester
CAS No.	252967-15-0
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	Methyl 2-Amino-2-hydroxy-2-phenylacetate; (R/S)-Methyl 2-Amino-2-hydroxy-2-phenylacetate; Mandelic acid, 2-amino-, methyl ester; α-Amino-α-hydroxybenzeneacetic acid methyl ester; Methyl α-amino-α-hydroxybenzeneacetate; 2-Amino-2-hydroxy-2-phenylacetic acid methyl ester; Amino-hydroxy-phenyl-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, A-Amino-2-Hydroxy-, Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We adhere to cGMP guidelines where applicable to ensure traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.