Description

Benzaldehyde, 5-Ethynyl-2-Hydroxy- (9Ci) is a specialized aromatic aldehyde derivative featuring both an ethynyl and a phenolic hydroxyl group, making it a versatile building block for advanced organic synthesis. This compound is valued for its dual functional handles, enabling selective modifications to create complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a precursor for novel catalysts and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and oncology research programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks (MOFs/COFs).
• Ligand & Catalyst Development: The ethynyl and phenolic groups allow for the creation of complex chelating ligands for transition metal catalysis.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and synthesizing complex natural product analogs.
• Fine Chemical Production: Acts as a precursor for dyes, flavors, and fragrances requiring specific aromatic-aldehyde functionality.

Basic Information

Product Name	Benzaldehyde, 5-Ethynyl-2-Hydroxy- (9Ci)
CAS No.	252771-08-7
Molecular Formula	C9H6O2
Molecular Weight	146.14 g/mol
Synonyms	5-Ethynyl-2-hydroxybenzaldehyde; 2-Hydroxy-5-ethynylbenzaldehyde; 5-Ethynylsalicylaldehyde; Salicylaldehyde, 5-ethynyl-; Benzaldehyde, 5-ethynyl-2-hydroxy-; 2-Hydroxy-5-(ethynyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 5-Ethynyl-2-Hydroxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.