Description

Ethanone, 1-(5-Amino-2-Methoxyphenyl)-2,2,2-Trifluoro- (9Ci) CAS NO 252580-28-2 is a specialized trifluoromethyl ketone derivative featuring both amino and methoxy functional groups on its aromatic ring. This unique molecular structure makes it a high-value intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and fine-tuning compound properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with trifluoromethyl motifs.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in organic and organometallic chemistry for the preparation of complex ligands used in catalysis.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on molecular properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and functional dyes due to its aromatic amine structure.

Basic Information

Product Name	Ethanone, 1-(5-Amino-2-Methoxyphenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	252580-28-2
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	1-(5-Amino-2-methoxyphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-amino-2-methoxyphenyl)ethanone; 5-Amino-2-methoxy-α,α,α-trifluoroacetophenone; 2-Methoxy-5-amino-α,α,α-trifluoroacetophenone; 2,2,2-Trifluoro-1-(5-amino-2-methoxyphenyl)ethan-1-one; 5-Amino-2-methoxybenzoyl trifluoromethane; Trifluoro(5-amino-2-methoxyphenyl)methanone
EINECS	Contact for details

Quality Control

Our high-purity Ethanone derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet rigorous R&D standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.