Description

Benzeneacetamide, -α--Hydroxy-2-(Trifluoromethyl)- is a specialized fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl-substituted benzyl alcohol structure, which is a key pharmacophore in medicinal chemistry for modulating lipophilicity, metabolic stability, and binding affinity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty monomers or ligands used in catalysis and advanced polymer development.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fluorine Chemistry Studies: A valuable substrate for academic and industrial research into new fluorination reactions and methodologies.

Basic Information

Product Name	Benzeneacetamide, -α--Hydroxy-2-(Trifluoromethyl)-
CAS No.	251366-94-6
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-(Trifluoromethyl)mandelamide; α-Hydroxy-2-(trifluoromethyl)benzeneacetamide; 2-Hydroxy-2-[2-(trifluoromethyl)phenyl]acetamide; (RS)-2-Hydroxy-2-[2-(trifluoromethyl)phenyl]acetamide; (±)-2-Hydroxy-2-(2-trifluoromethylphenyl)acetamide; 2-(2-Trifluoromethylphenyl)-2-hydroxyacetamide; NSC 405124
EINECS	Contact for details

Quality Control

Our Benzeneacetamide, -α--Hydroxy-2-(Trifluoromethyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, with each shipment. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request and are essential for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.