Description

5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Benzaldehyde is a versatile and highly functionalized aromatic aldehyde, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring bromo, hydroxy, and trifluoromethyl substituents, makes it an invaluable building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular scaffolds for drug discovery, crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and dyes due to its electron-withdrawing and steric properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories engaged in novel organic synthesis and methodology development.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Benzaldehyde
CAS No.	251300-30-8
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	3-(Trifluoromethyl)-5-bromosalicylaldehyde; 5-Bromo-3-(trifluoromethyl)salicylaldehyde; 2-Hydroxy-5-bromo-3-(trifluoromethyl)benzaldehyde; 5-Bromo-2-hydroxy-α,α,α-trifluoro-m-tolualdehyde; Benzaldehyde, 5-bromo-2-hydroxy-3-(trifluoromethyl)-; 5-Bromo-3-trifluoromethylsalicylaldehyde; 5-Bromo-2-hydroxy-3-trifluoromethylbenzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.