Description

Methanone, 1H-Benzimidazol-6-Yl[4-[(2E)-3-Phenyl-2-Propen-1-Yl]-1-Piperazinyl]- is a specialized organic compound featuring a benzimidazole core linked to a piperazine moiety via a ketone bridge, with a cinnamyl substituent. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Biochemical Research: Used as a reference standard or a precursor in the study of enzyme inhibition and receptor binding assays.
• Organic Synthesis: Employed in academic and industrial research for constructing complex heterocyclic frameworks due to its reactive functional groups.
• Agrochemical Development: Potential use as an intermediate in the creation of new crop protection agents with specific biological activity.
• Material Science Research: Investigated for the development of organic semiconductors or photoactive materials given its conjugated system.

Basic Information

Item	Detail
Product Name	Methanone, 1H-Benzimidazol-6-Yl[4-[(2E)-3-Phenyl-2-Propen-1-Yl]-1-Piperazinyl]-
CAS No.	251106-30-6
Molecular Formula	C27H26N4O
Molecular Weight	422.52 g/mol
Synonyms	6-[(4-Cinnamyl-1-piperazinyl)carbonyl]-1H-benzimidazole; 1H-Benzimidazol-6-yl[4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]methanone; (E)-1H-Benzimidazol-6-yl[4-(3-phenylallyl)piperazin-1-yl]methanone; 6-(4-Cinnamylpiperazine-1-carbonyl)-1H-benzimidazole; Cinnamyl-piperazinyl-benzimidazolyl methanone; 251106-30-6; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.