Description

Methyl 5-Bromo-2-Chlorobenzoate is a high-purity, versatile benzoate ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with orthogonal reactive sites, enabling precise molecular construction for complex targets. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated benzoate scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating specialized aromatic compounds used in electronic displays and optoelectronic devices.
• Organic Ligand Preparation: Utilized in the development of ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the bromo and chloro substituents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	Methyl 5-Bromo-2-Chlorobenzoate
CAS No.	251085-87-7
Molecular Formula	C8H6BrClO2
Molecular Weight	249.49 g/mol
Synonyms	5-Bromo-2-chlorobenzoic acid methyl ester; Methyl 5-bromo-2-chlorobenzoate; Benzoic acid, 5-bromo-2-chloro-, methyl ester; 2-Chloro-5-bromobenzoic acid methyl ester; Methyl 2-chloro-5-bromobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Chlorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.