Description

5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydrothieno[3,4-B][1,4]Dioxine is a high-value, advanced pharmaceutical intermediate and organic building block. This compound is critical for Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex conjugated molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Electronics: Precursor for conjugated polymers and small molecules used in Organic Light-Emitting Diodes (OLEDs), Organic Photovoltaics (OPVs), and field-effect transistors (OFETs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Enables the creation of functionalized thiophene-based materials with tailored optical and electronic properties.
• Chemical Synthesis: A versatile boronic ester pinacol ester for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Serves as a precursor for complex ligands used in homogeneous catalysis.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydrothieno[3,4-B][1,4]Dioxine
CAS No.	250726-93-3
Molecular Formula	C14H19BO4S
Molecular Weight	294.17 g/mol
Synonyms	2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrothieno[3,4-b][1,4]dioxine; EDOT-BPin; 3,4-ethylenedioxythiophene-2-boronic acid pinacol ester; 5-(Pinacolatoboryl)-2,3-dihydrothieno[3,4-b][1,4]dioxine; 2,3-Dihydro[1,4]dioxino[2,3-c]thiophene-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydrothieno[3,4-B][1,4]Dioxine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for advanced R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.