Description

trans-4-(2-Propyn-1-Yl)-Cyclohexanecarboxylic Acid Methyl Ester is a high-value, functionalized cyclohexane derivative featuring a propargyl side chain, making it a versatile synthon for advanced organic synthesis. Its core value lies in its role as a key pharmaceutical intermediate and a crucial building block for constructing complex molecular architectures. This compound is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and material science sectors, where it is used to develop new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and plant growth regulators with specific activity profiles.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced functional materials.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex organic molecules and as a ligand precursor in catalytic systems.
• Click Chemistry: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and polymer chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	trans-4-(2-Propyn-1-Yl)-Cyclohexanecarboxylic Acid Methyl Ester
CAS No.	250682-81-6
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	Methyl trans-4-(prop-2-yn-1-yl)cyclohexanecarboxylate; trans-4-(Prop-2-yn-1-yl)cyclohexanecarboxylic acid methyl ester; Methyl 4-(2-propynyl)cyclohexanecarboxylate (trans); 4-(Prop-2-yn-1-yl)cyclohexanecarboxylic Acid Methyl Ester; Methyl 4-(prop-2-yn-1-yl)cyclohexanecarboxylate; Cyclohexanecarboxylic acid, 4-(2-propyn-1-yl)-, methyl ester, trans-; 250682-81-6
EINECS	Contact for details

Quality Control

Our trans-4-(2-Propyn-1-Yl)-Cyclohexanecarboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent isomeric composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (GC/HPLC)	≥ 95.0% (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.