Description

1-Propanone, 2-Fluoro-1-(4-Methoxyphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its unique fluorine and methoxy-substituted structure enables precise modulation of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in therapeutic areas targeting the central nervous system (CNS) and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Liquid Crystal & OLED Development: Employed in the research and production of fluorinated components for display and lighting technologies.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	1-Propanone, 2-Fluoro-1-(4-Methoxyphenyl)- (9Ci)
CAS No.	250277-92-0
Molecular Formula	C10H11FO2
Molecular Weight	182.19 g/mol
Synonyms	2-Fluoro-1-(4-methoxyphenyl)propan-1-one; 4'-Methoxy-2-fluoropropiophenone; 1-(4-Methoxyphenyl)-2-fluoropropan-1-one; 2-Fluoro-4'-methoxypropiophenone; α-Fluoro-4-methoxypropiophenone; 2-Fluoro-1-(p-methoxyphenyl)-1-propanone; 250277-92-0; 2-Fluoro-1-(4-methoxyphenyl)propan-1-one (9CI)
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Fluoro-1-(4-Methoxyphenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, TSCA) ensures a reliable supply for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.