Description

6-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-5-Carbaldehyde is a high-value, functionalized benzodioxine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and an aldehyde group, makes it an exceptionally versatile building block for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the benzodioxine scaffold for bioactive molecule design.
• Material Science & Organic Electronics: Serves as a building block for creating conjugated polymers, organic semiconductors, and light-emitting materials due to its electron-rich aromatic system.
• Ligand & Catalyst Development: The aldehyde group allows for facile derivatization into Schiff bases and other chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Utilized in the creation of fluorescent probes, affinity labels, and other tools for studying biological systems.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	6-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-5-Carbaldehyde
CAS No.	249636-65-5
Molecular Formula	C9H7BrO3
Molecular Weight	243.06 g/mol
Synonyms	6-Bromo-2,3-dihydro-1,4-benzodioxine-5-carboxaldehyde; 5-Bromo-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde; 6-Bromo-1,4-benzodioxane-5-carbaldehyde; 249636-65-5; 6-Bromobenzodioxine-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Dihydrobenzo[B][1,4]Dioxine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.