Description

5-(4-Fluorophenyl)Thiophene-2-Carboxaldehyde is a high-purity organic building block featuring a thiophene core substituted with a fluorinated aromatic aldehyde group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the bioactivity of the thiophene and fluorophenyl motifs.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes for diagnostic and imaging applications.

Basic Information

Item	Detail
Product Name	5-(4-Fluorophenyl)Thiophene-2-Carboxaldehyde
CAS No.	249504-38-9
Molecular Formula	C11H7FOS
Molecular Weight	206.24 g/mol
Synonyms	5-(4-Fluorophenyl)-2-thiophenecarboxaldehyde; 2-Formyl-5-(4-fluorophenyl)thiophene; 4-Fluoro-5-(2-thienyl)benzaldehyde; 5-(p-Fluorophenyl)thiophene-2-carbaldehyde; 249504-38-9; 5-(4-Fluorophenyl)-2-thiophenecarbaldehyde; 5-(4-Fluorophenyl)thiophene-2-aldehyde
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Thiophene-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.