Description

1-(2-Fluoro-4-Iodophenyl)Ethanone is a high-purity fluorinated and iodinated aromatic ketone, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications in the development of complex active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and iodine substituents can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a substrate for further functionalization to create diverse chemical libraries for screening.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	1-(2-Fluoro-4-Iodophenyl)Ethanone
CAS No.	249291-84-7
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	2'-Fluoro-4'-Iodoacetophenone; 1-(2-Fluoro-4-iodophenyl)ethan-1-one; 2-Fluoro-4-iodoacetophenone; 4'-Iodo-2'-fluoroacetophenone; 1-Acetyl-2-fluoro-4-iodobenzene; 2-Fluoro-4-iodophenylethanone; α-Fluoro-α'-iodoacetophenone (isomer specific); 249291-84-7
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-Iodophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.