Description

2',4',6'-Trihydroxyacetophenone Monohydrate is a specialized polyphenolic ketone compound, recognized for its role as a key synthetic intermediate and building block in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides specific reactivity and functionality for constructing complex molecular architectures. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in flavonoid and polyphenol-related therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and plant growth regulators, leveraging its phenolic structure.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, UV absorbers, and other specialty chemicals requiring a trihydroxyacetophenone core.
• Biochemical Research: Employed as a standard or reagent in studies related to antioxidant activity, enzyme inhibition, and natural product synthesis.
• Cosmetic Ingredient Development: Investigated for use in skincare formulations due to its potential antioxidant and UV-protective properties derived from its polyphenolic nature.

Basic Information

Product Name	2',4',6'-Trihydroxyacetophenone Monohydrate
CAS No.	249278-28-2
Molecular Formula	C8H8O4 • H2O
Molecular Weight	186.16 g/mol (Anhydrous basis: 168.15)
Synonyms	1-(2,4,6-Trihydroxyphenyl)ethanone monohydrate; 2',4',6'-Trihydroxyacetophenone hydrate; Phloroacetophenone monohydrate; 2,4,6-Trihydroxyacetophenone monohydrate; 1-Acetyl-2,4,6-trihydroxybenzene monohydrate; THAP monohydrate; Acetophenone, 2',4',6'-trihydroxy-, monohydrate
EINECS	Contact for details

Quality Control

Our 2',4',6'-Trihydroxyacetophenone Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, which include data from HPLC, NMR, and other relevant analytical techniques to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	8.0 - 10.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.