Description

trans-4-{[(Phenylsulfonyl)Amino]-Methyl}Cyclohexanecarboxylic Acid is a high-purity, functionalized cyclohexane derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetic Chemistry: Serves as a constrained, non-natural amino acid analog for designing bioactive peptides with enhanced stability and potency.
• Ligand and Catalyst Development: Used in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed as a building block for novel, high-value crop protection agents and herbicides.
• Material Science Precursor: Functions as a monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or mechanical properties.
• Academic and Industrial R&D: A valuable tool compound for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Detail
Product Name	trans-4-{[(Phenylsulfonyl)Amino]-Methyl}Cyclohexanecarboxylic Acid
CAS No.	247936-90-9
Molecular Formula	C15H21NO4S
Molecular Weight	311.40 g/mol
Synonyms	trans-4-[(Phenylsulfonylamino)methyl]cyclohexanecarboxylic acid; (1r,4r)-4-[[(Phenylsulfonyl)amino]methyl]cyclohexanecarboxylic acid; 4-[[(Phenylsulfonyl)amino]methyl]cyclohexanecarboxylic acid (trans); 4-[(Phenylsulfonylamino)methyl]cyclohexanecarboxylic acid; 247936-90-9; trans-4-[(Phenylsulfonylamino)methyl]cyclohexane-1-carboxylic acid; (trans)-4-[[(Phenylsulfonyl)amino]methyl]cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our trans-4-{[(Phenylsulfonyl)Amino]-Methyl}Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.