Description

2-(2,5-Dimethoxyphenyl)-1,3,2-Dioxaborinane CAS NO 247586-32-9 is a specialized organoboron reagent featuring a protected boronic acid moiety. This compound is a critical intermediate in modern synthetic organic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable, air- and moisture-tolerant boronic ester reagent for palladium-catalyzed cross-coupling with aryl halides or triflates.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in exploring new chemical spaces and optimizing synthetic routes.
• Ligand and Catalyst Preparation: Can be utilized to synthesize novel bidentate or polydentate ligands for catalysis.

Basic Information

Product Name	2-(2,5-Dimethoxyphenyl)-1,3,2-Dioxaborinane
CAS No.	247586-32-9
Molecular Formula	C12H17BO4
Molecular Weight	236.07 g/mol
Synonyms	2,5-Dimethoxyphenyl-1,3,2-dioxaborinane; (2,5-Dimethoxyphenyl)-1,3,2-dioxaborinane; 2,5-Dimethoxyphenylboronic acid 1,3-propanediol ester; 2,5-Dimethoxyphenylboronic acid pinacol ester (common misnomer, correct class is dioxaborinane); 1,3,2-Dioxaborinane, 2-(2,5-dimethoxyphenyl)-; Boronic acid, B-(2,5-dimethoxyphenyl)-, 1,3-propanediol ester
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethoxyphenyl)-1,3,2-Dioxaborinane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.