Description

4-(Bromomethyl)-1-Chloro-2-Ethoxybenzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and chloro substituents on an ethoxybenzene core, makes it a critical precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables efficient functionalization and serves as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for introducing functionalized benzyl groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalytic systems.
• Material Science Research: Employed in the creation of novel organic frameworks and functional polymers.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags for biochemical research.

Basic Information

Item	Details
Product Name	4-(Bromomethyl)-1-Chloro-2-Ethoxybenzene
CAS No.	247569-90-0
Molecular Formula	C9H10BrClO
Molecular Weight	249.53 g/mol
Synonyms	1-Chloro-2-ethoxy-4-(bromomethyl)benzene; 2-Chloro-5-(bromomethyl)phenetole; 4-Bromomethyl-1-chloro-2-ethoxybenzene; 1-Chloro-4-(bromomethyl)-2-ethoxybenzene; 2-Ethoxy-5-(bromomethyl)chlorobenzene; 5-(Bromomethyl)-2-chlorophenetole; (2-Chloro-5-ethoxyphenyl)methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-1-Chloro-2-Ethoxybenzene is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.