Description

6,7-Difluoro-1H-Indole-2-Carboxylic Acid is a high-value fluorinated indole derivative, a crucial building block in modern synthetic chemistry. Its core value lies in its unique molecular structure, which serves as a versatile scaffold for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides where the difluoro-indole core can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functional component in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to its fluorescent potential and ability to interact with biological targets.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis: A starting material for the bespoke synthesis of more complex fluorinated heterocycles for specialized client projects.

Basic Information

Product Name	6,7-Difluoro-1H-Indole-2-Carboxylic Acid
CAS No.	247564-68-7
Molecular Formula	C9H5F2NO2
Molecular Weight	197.14 g/mol
Synonyms	6,7-Difluoroindole-2-carboxylic acid; 2-Carboxy-6,7-difluoroindole; 1H-Indole-2-carboxylic acid, 6,7-difluoro-; 6,7-Difluoro-1H-indole-2-carboxylic acid; 247564-68-7; 6,7-Difluorindol-2-carbonsäure (German); Acide 6,7-difluoro-1H-indole-2-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 6,7-Difluoro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.