Description

tert-Butyl 3-Formylbenzoate is a high-purity aromatic ester derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a formyl group and a tert-butyl ester, makes it an invaluable precursor for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material or advanced intermediate in the synthesis of novel drug candidates, particularly those requiring a benzoic acid derivative scaffold.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where specific aromatic substitution patterns are required.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the creation of monomers for specialty polymers, including photosensitive resins and high-performance engineering plastics.
• Chemical Research: Utilized in academic and industrial laboratories for method development and exploring new chemical reactions, such as cross-coupling and condensation reactions.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring a formyl benzoate structure.

Basic Information

Product Name	tert-Butyl 3-Formylbenzoate
CAS No.	247186-56-7
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	3-(tert-Butoxycarbonyl)benzaldehyde; Benzoic acid, 3-formyl-, 1,1-dimethylethyl ester; tert-Butyl m-formylbenzoate; 3-Formylbenzoic acid tert-butyl ester; 1,1-Dimethylethyl 3-formylbenzoate; m-Formylbenzoic Acid tert-Butyl Ester; 3-Carboxybenzaldehyde tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Formylbenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.