Description

Ethyl 3-[4-(tert-Butyl)Phenyl]-2-Cyanoacrylate is a specialized cyanoacrylate derivative, a high-value intermediate in advanced organic synthesis. This compound is prized for its unique molecular architecture, which combines a cyanoacrylate core with a sterically hindered tert-butylphenyl group, offering distinct reactivity and stability profiles. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the tert-butyl group can enhance lipophilicity and biological activity.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for specialty polymers, adhesives, and coatings requiring specific thermal or chemical resistance.
• Organic Electronics: Investigated as a precursor for electron-transport materials or as a component in the fabrication of organic light-emitting diodes (OLEDs) and photovoltaics.
• Chemical Research: Employed in academic and industrial R&D for methodology development, such as in Michael addition reactions or cyclization processes, due to its activated double bond.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of advanced chromophores and functional dyes for high-performance applications.

Basic Information

Item	Details
Product Name	Ethyl 3-[4-(tert-Butyl)Phenyl]-2-Cyanoacrylate
CAS No.	247099-46-3
Molecular Formula	C16H19NO2
Molecular Weight	257.33 g/mol
Synonyms	Ethyl (2E)-3-[4-(1,1-Dimethylethyl)phenyl]-2-cyano-2-propenoate; Ethyl (E)-3-(4-tert-Butylphenyl)-2-cyanoacrylate; 2-Propenoic acid, 2-cyano-3-[4-(1,1-dimethylethyl)phenyl]-, ethyl ester; Ethyl 3-(p-tert-Butylphenyl)-2-cyanoacrylate; 4-tert-Butylbenzylidenecyanoacetic acid ethyl ester; (E)-Ethyl 3-(4-(tert-butyl)phenyl)-2-cyanoacrylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 3-[4-(tert-Butyl)Phenyl]-2-Cyanoacrylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure consistency and reliability. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.