Description

2-Pyrrolidinone, 1-Acetyl-5-Fluoro-3-Methyl- (9Ci) CAS NO 246181-65-7 is a high-value, fluorinated pyrrolidinone derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorinated pyrrolidinone structure can enhance biological activity and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Investigated as a monomer or additive for developing specialty polymers with unique thermal or solubility properties.

Basic Information

Product Name	2-Pyrrolidinone, 1-Acetyl-5-Fluoro-3-Methyl- (9Ci)
CAS No.	246181-65-7
Molecular Formula	C7H10FNO2
Molecular Weight	159.16 g/mol
Synonyms	1-Acetyl-5-fluoro-3-methylpyrrolidin-2-one; 5-Fluoro-3-methyl-1-(acetyl)-2-pyrrolidinone; N-Acetyl-5-fluoro-3-methyl-2-pyrrolidinone; 1-Acetyl-5-fluoro-3-methyl-2-pyrrolidinone; 5-Fluoro-3-methyl-1-acetyl-2-pyrrolidinone; 246181-65-7; 2-Pyrrolidinone, 1-acetyl-5-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinone, 1-Acetyl-5-Fluoro-3-Methyl- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.