Description

2-Bromo-1-Bromomethyl-4-tert-Butyl-Benzene is a high-purity brominated aromatic compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of two bromine atoms, which provide distinct reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the tert-butyl and bromomethyl groups contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers with tailored electronic or photophysical properties.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-1-Bromomethyl-4-tert-Butyl-Benzene
CAS No.	246139-76-4
Molecular Formula	C11H14Br2
Molecular Weight	306.04 g/mol
Synonyms	1,2-Bis(bromomethyl)-4-tert-butylbenzene; 4-tert-Butyl-1,2-bis(bromomethyl)benzene; 4-(tert-Butyl)-1,2-bis(bromomethyl)benzene; 2-Bromo-1-(bromomethyl)-4-(tert-butyl)benzene; 1,2-Dibromomethyl-4-tert-butylbenzene; 4-tert-Butyl-o-xylene-α,α'-dibromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Bromomethyl-4-tert-Butyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.