Description

2-(4,4,5,5,6,6,6-Heptafluorohexyl)Malonic Acid is a specialized fluorinated malonic acid derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a perfluoroalkyl chain, imparts valuable properties such as enhanced lipophilicity and chemical stability, making it a critical intermediate for high-performance materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where the introduction of fluorine atoms is a strategic design element to optimize bioactivity and material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in creating fluorinated analogs with improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorinated side chain can enhance biological activity and environmental persistence.
• Specialty Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing fluorinated polymers, coatings, and elastomers with superior chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Surface Modification Reagent: Utilized to introduce fluorinated groups onto surfaces or molecules, imparting hydrophobic and oleophobic properties for advanced material coatings.
• Organic Synthesis & Medicinal Chemistry Research: A versatile building block in academic and industrial R&D for constructing complex, fluorinated molecular architectures.

Basic Information

Product Name	2-(4,4,5,5,6,6,6-Heptafluorohexyl)Malonic Acid
CAS No.	244022-64-8
Molecular Formula	C11H9F7O4
Molecular Weight	326.18 g/mol
Synonyms	2-(Perfluorohexyl)malonic Acid; 2-(4,4,5,5,6,6,6-Heptafluorohexyl)propanedioic Acid; 2-(1H,1H-Perfluorohexyl)malonic Acid; Heptafluorohexylmalonic Acid; Malonic Acid, 2-(4,4,5,5,6,6,6-heptafluorohexyl)-; 2-(Perfluoro-n-hexyl)malonic Acid; (4,4,5,5,6,6,6-Heptafluorohexyl)malonic Acid
EINECS	Contact for details

Quality Control

Our production of 2-(4,4,5,5,6,6,6-Heptafluorohexyl)Malonic Acid adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific research or industrial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.