Description

4,5,5,5-Tetrafluoro-4-(trifluoromethyl)pentanoic acid is a high-value, multi-fluorinated carboxylic acid building block. This compound is critical for introducing perfluoroalkyl groups into target molecules, significantly altering their physicochemical properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique fluorinated structure can enhance metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting improved pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine incorporation can increase efficacy and environmental persistence.
• Advanced Material Precursor: Serves as a building block for fluorinated polymers, surfactants, and liquid crystals, imparting oil- and water-repellency, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex fluorinated organic molecules via reactions at the carboxylic acid group.
• Ligand and Catalyst Development: Useful for modifying ligands and catalysts to create fluorinated analogs with unique solubility and reactivity characteristics.

Basic Information

Product Name	4,5,5,5-Tetrafluoro-4-(trifluoromethyl)pentanoic Acid
CAS No.	243139-62-0
Molecular Formula	C6H4F7O2
Molecular Weight	226.08 g/mol
Synonyms	4-(Trifluoromethyl)-4,5,5,5-tetrafluoropentanoic acid; 4,5,5,5-Tetrafluoro-4-(trifluoromethyl)valeric acid; 4,5,5,5-Tetrafluoro-4-trifluoromethylpentanoic acid; Pentanoic acid, 4,5,5,5-tetrafluoro-4-(trifluoromethyl)-; 4,5,5,5-Tetrafluoro-4-(trifluoromethyl)pentanoic acid; 4,5,5,5-Tetrafluoro-4-(trifluoromethyl)valeric acid; 4-(Trifluoromethyl)-4,5,5,5-tetrafluorovaleric acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We provide comprehensive analytical data to support your development work. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch, ensuring full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.