Description

4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)pentanoic acid is a highly fluorinated carboxylic acid building block of significant interest in advanced material science and pharmaceutical chemistry. Its unique structure, featuring a perfluorinated ether side chain, makes it a valuable precursor for synthesizing compounds with enhanced stability, lipophilicity, and specific electronic properties. This specialty chemical is primarily utilized by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries seeking to incorporate fluorinated motifs into novel molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs) with improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Fluorinated Surfactant & Polymer Precursor: Acts as a building block for creating specialty surfactants, coatings, and polymers with oil- and water-repellent (omniphobic) characteristics.
• Liquid Crystal & Electronic Material Research: Employed in the synthesis of fluorinated liquid crystals and organic semiconductors for display and electronic applications.
• Catalyst Ligand Modification: Used to introduce fluorinated groups into ligand systems for catalysis, potentially altering solubility and reactivity in fluorous media.

Basic Information

Product Name	4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)pentanoic Acid
CAS No.	243139-58-4
Molecular Formula	C6H4F7O3
Molecular Weight	242.08 g/mol
Synonyms	4-(Trifluoromethoxy)-4,5,5,5-tetrafluoropentanoic acid; 4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)valeric acid; Pentanoic acid, 4,5,5,5-tetrafluoro-4-(trifluoromethoxy)-; 4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)pentanoic acid; 243139-58-4; FC-4-Pentanoic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of 4,5,5,5-Tetrafluoro-4-(trifluoromethoxy)pentanoic acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and meet exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its acidic and fluoride-containing nature, ensure containers are clearly labeled and stored on secondary containment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.