Description

Benzyl 3-((Chlorosulfonyl)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive chlorosulfonyl and carboxylate functional groups. This compound is critical for medicinal chemists in the research and development of novel active pharmaceutical ingredients (APIs), particularly in the synthesis of complex molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable and consistent building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis from laboratory to pilot plant scale.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds for client projects.
• Bioconjugation Chemistry: The reactive chlorosulfonyl group can be utilized for linking molecules to proteins, peptides, or other biomolecules in drug delivery system research.

Basic Information

Item	Details
Product Name	Benzyl 3-((Chlorosulfonyl)Methyl)Piperidine-1-Carboxylate
CAS No.	242459-83-2
Molecular Formula	C15H20ClNO4S
Molecular Weight	345.84 g/mol
Synonyms	1-(Benzyloxycarbonyl)-3-(chlorosulfonylmethyl)piperidine; 3-((Chlorosulfonyl)Methyl)-1-Carbobenzyloxypiperidine; 1-CBZ-3-(Chlorosulfonylmethyl)piperidine; N-CBZ-3-(Chlorosulfonylmethyl)piperidine; Benzyl 3-(Chlorosulfonylmethyl)piperidine-1-carboxylate; 1-Carbobenzyloxy-3-(chlorosulfonylmethyl)piperidine; 242459-83-2; Piperidine-1-carboxylic acid, 3-[(chlorosulfonyl)methyl]-, benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 3-((Chlorosulfonyl)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.