Description

1-(4-Iodo-Phenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carbaldehyde is a high-purity, functionalized pyrrole derivative characterized by its aldehyde and iodophenyl substituents. This compound serves as a versatile and critical advanced pharmaceutical intermediate (API) and organic synthesis building block for constructing complex molecular architectures. It is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require precise, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl systems.
• Ligand Synthesis: Utilized for preparing novel chelating ligands for catalysis and metal-organic chemistry.
• Fluorescent Probe Development: The pyrrole-aldehyde structure can be used to create fluorophores and molecular sensors for biochemical assays.

Basic Information

Item	Details
Product Name	1-(4-Iodo-Phenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carbaldehyde
CAS No.	241488-81-3
Molecular Formula	C13H12INO
Molecular Weight	325.15 g/mol
Synonyms	4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)iodobenzene; 1-(4-Iodophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxaldehyde; 2,5-Dimethyl-1-(4-iodophenyl)-1H-pyrrole-3-carbaldehyde; 1H-Pyrrole-3-carboxaldehyde, 1-(4-iodophenyl)-2,5-dimethyl-; 4-Iodo-2,5-dimethyl-1H-pyrrole-3-carbaldehyde phenyl derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Iodo-Phenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.