Description

4'-Fluoro-2'-(Trifluoromethyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the trifluoromethyl and fluoro groups impart desirable properties.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic electronic materials that benefit from fluorinated aromatic structures.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for use in custom synthesis projects and scale-up processes for client-specific molecules.

Basic Information

Product Name	4'-Fluoro-2'-(Trifluoromethyl)Propiophenone
CAS No.	239107-26-7
Molecular Formula	C10H6F4O
Molecular Weight	218.15 g/mol
Synonyms	1-(4-Fluoro-2-(trifluoromethyl)phenyl)propan-1-one; 4-Fluoro-2-(trifluoromethyl)propiophenone; 1-Propanone, 1-[4-fluoro-2-(trifluoromethyl)phenyl]-; 2'-Trifluoromethyl-4'-fluoropropiophenone; 4-Fluoro-α-ethyl-2-(trifluoromethyl)benzyl alcohol (keto form); α-Ethyl-4-fluoro-2-(trifluoromethyl)benzyl ketone
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-2'-(Trifluoromethyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.