Description

4-Fluoro-3-(trifluoromethyl)benzophenone is a high-value fluorinated aromatic ketone building block. This compound matters for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to create specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex, fluorinated aromatic structures via reactions like Friedel-Crafts acylation or nucleophilic substitution.
• Material Science Research: Investigated for its potential in creating novel coatings, adhesives, and high-performance materials with specific surface properties.

Basic Information

Product Name	4-Fluoro-3-(trifluoromethyl)benzophenone
CAS No.	239087-04-8
Molecular Formula	C14H8F4O
Molecular Weight	268.21 g/mol
Synonyms	4-Fluoro-3-(trifluoromethyl)benzophenone; [4-Fluoro-3-(trifluoromethyl)phenyl](phenyl)methanone; 4-Fluoro-α,α,α-trifluoro-m-benzophenone; 3-Trifluoromethyl-4-fluorobenzophenone; Benzophenone, 4-fluoro-3-(trifluoromethyl)-; (4-Fluoro-3-trifluoromethylphenyl)phenylmethanone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(trifluoromethyl)benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.