Description

3,4-Difluoro-5-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-fluorinated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both difluoro and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the fluorine atoms improve compound efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a fluorinated building block for electronic chemicals used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of fluorinated charge-transport or emissive layer materials.
• Cross-Coupling Reactions: Acts as an electrophilic benzylating agent in palladium-catalyzed and other metal-mediated coupling reactions.
• Material Science Research: Utilized in creating novel fluorinated polymers and specialty chemicals with unique surface properties.

Basic Information

Product Name	3,4-Difluoro-5-(Trifluoromethyl)Benzyl Bromide
CAS No.	239079-92-6
Molecular Formula	C9H4BrF5
Molecular Weight	287.03 g/mol
Synonyms	1-(Bromomethyl)-3,4-difluoro-5-(trifluoromethyl)benzene; (3,4-Difluoro-5-(trifluoromethyl)phenyl)methyl bromide; 5-(Bromomethyl)-1,2-difluoro-3-(trifluoromethyl)benzene; α-Bromo-3,4-difluoro-5-(trifluoromethyl)toluene; 3,4-Difluoro-α-bromo-α,α,α-trifluoro-p-xylene; Benzene, 1-(bromomethyl)-3,4-difluoro-5-(trifluoromethyl)-; 239079-92-6
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-5-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.