Description

2',4'-Bis(Trifluoromethyl)Acetophenone 98 is a high-purity, fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of trifluoromethyl groups is critical for modulating biological activity and physicochemical properties. Industries requiring sophisticated fluorination chemistry, such as pharmaceutical R&D, agrochemical manufacturing, and materials science, rely on this high-quality intermediate to drive innovation in their product pipelines.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethyl group enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorinated compounds often provide improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), contributing to enhanced performance and durability.
• Advanced Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers and coatings, imparting unique properties such as chemical resistance, low surface energy, and thermal stability.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination methodologies, cross-coupling reactions, and the construction of complex molecular architectures.
• Ligand & Catalyst Development: Used to synthesize novel fluorinated ligands for metal catalysts, which can improve selectivity and efficiency in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2',4'-Bis(Trifluoromethyl)Acetophenone 98
CAS No.	237069-82-8
Molecular Formula	C10H5F6O
Molecular Weight	246.14 g/mol
Synonyms	1-[2,4-Bis(trifluoromethyl)phenyl]ethanone; 2',4'-Bis(trifluoromethyl)acetophenone; 2,4-Bis(trifluoromethyl)acetophenone; α,α,α,α',α',α'-Hexafluoro-2,4-dimethylacetophenone; 1-(2,4-Bis(trifluoromethyl)phenyl)ethan-1-one; Acetophenone, 2',4'-bis(trifluoromethyl)-; Ethanone, 1-[2,4-bis(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2',4'-Bis(Trifluoromethyl)Acetophenone 98 is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the purity and identity meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with customer requirements for research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.