Description

2,2-Oxiranediol,3-Fluoro-3-(Trifluoromethyl)-,(3R)-(9Ci) is a high-value, chiral fluorinated epoxide derivative, serving as a critical synthetic intermediate. Its unique stereochemistry and trifluoromethyl group make it indispensable for introducing fluorine-containing motifs into target molecules, which is a key strategy in modern drug design to enhance metabolic stability and bioavailability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Advanced Material Precursor: Employed in the development of specialty polymers and coatings with tailored surface properties and enhanced chemical resistance.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	2,2-Oxiranediol,3-Fluoro-3-(Trifluoromethyl)-,(3R)-(9Ci)
CAS No.	232260-61-6
Molecular Formula	C4H4F4O2
Molecular Weight	160.07 g/mol
Synonyms	(3R)-3-Fluoro-3-(trifluoromethyl)oxirane-2,2-diol; 3-Fluoro-3-(trifluoromethyl)oxiran-2-ol; (R)-3-Fluoro-3-(trifluoromethyl)glycidol; (R)-3-Fluoro-3-trifluoromethylglycidol; 3-Fluoro-3-(trifluoromethyl)-2-oxiranemethanol, (2R)-; 232260-61-6; Fluorinated chiral epoxide; Trifluoromethyl glycidol derivative
EINECS	Contact for details

Quality Control

Our 2,2-Oxiranediol,3-Fluoro-3-(Trifluoromethyl)-,(3Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.