Description

Ethanone, 1-[6-(Dimethylamino)-3-Pyridinyl]-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a dimethylaminopyridine moiety, making it a valuable building block in advanced organic synthesis. This compound is significant for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Ethanone, 1-[6-(Dimethylamino)-3-Pyridinyl]-2,2,2-Trifluoro- (9Ci)
CAS No.	230305-78-9
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	1-[6-(Dimethylamino)-3-pyridinyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-[6-(dimethylamino)-3-pyridinyl]ethanone; 6-(Dimethylamino)-3-pyridinyl trifluoromethyl ketone; 6-Dimethylamino-3-pyridyl trifluoromethyl ketone; 6-DMAP-3-TFK; 230305-78-9; 1-(6-(Dimethylamino)pyridin-3-yl)-2,2,2-trifluoroethan-1-one
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[6-(Dimethylamino)-3-Pyridinyl]-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.