Description

Ethanone, 1-[5-(Dimethylamino)-2-Pyridinyl]-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a dimethylaminopyridine moiety, making it a valuable building block in advanced organic synthesis. This compound is significant for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its unique structure can impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate sophisticated fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring fluorinated components for enhanced bioavailability and metabolic resistance.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and environmental stability.
• Material Science: Acts as a monomer or cross-linking agent in the creation of advanced polymers and coatings with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for developing enzyme inhibitors or receptor modulators.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic additions, and other transformations to construct complex molecular architectures.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the synthesis and application of organofluorine compounds.

Basic Information

Product Name	Ethanone, 1-[5-(Dimethylamino)-2-Pyridinyl]-2,2,2-Trifluoro- (9Ci)
CAS No.	230305-75-6
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	1-[5-(Dimethylamino)-2-pyridinyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-[5-(dimethylamino)-2-pyridinyl]ethanone; 5-(Dimethylamino)-2-(trifluoroacetyl)pyridine; 2-(Trifluoroacetyl)-5-(dimethylamino)pyridine; 1-(5-(Dimethylamino)pyridin-2-yl)-2,2,2-trifluoroethan-1-one; 230305-75-6; TFAP-DMAP
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[5-(Dimethylamino)-2-Pyridinyl]-2,2,2-Trifluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.