Description

Bis[(+)-Pinanediolato]Diboron CAS NO 230299-17-9 is a high-purity, chiral organoboron reagent widely used as a key intermediate in advanced organic synthesis. Its primary value lies in enabling highly stereoselective transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for asymmetric synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A versatile catalyst precursor for forming carbon-carbon bonds under mild conditions.
• Asymmetric Synthesis of Pharmaceutical Intermediates: Critical for constructing chiral centers in active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, oncology, and infectious diseases.
• Preparation of Boronic Esters and Acids: Serves as a protected boronic acid equivalent for further functionalization in multi-step syntheses.
• Catalyst Development in Homogeneous Catalysis: Used in the research and development of novel chiral ligands and catalysts.
• Agrochemical Intermediate Synthesis: Employed in the production of chiral herbicides, fungicides, and plant growth regulators.
• Material Science Research: A building block for creating boron-containing polymers and advanced organic electronic materials.

Basic Information

Product Name	Bis[(+)-Pinanediolato]Diboron
CAS No.	230299-17-9
Molecular Formula	C20H32B2O4
Molecular Weight	357.09 g/mol
Synonyms	(+)-Pinanediol Diboron; Bis[(+)-Pinanediolato]Diboron; (+)-Pinanediol Diboronate; Diboron Pinanediol Ester; (R,R)-2,2'-(1,2-Diborylethane-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (related IUPAC); Chiral Pinanediol Diboron Reagent; B2(pin)2 (Chiral variant); 230299-17-9
EINECS	Contact for details

Quality Control

Our Bis[(+)-Pinanediolato]Diboron is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.