Description

Bis[(-)Pinanediolato]Diboron is a high-purity, chiral organoboron reagent essential for modern synthetic chemistry. Its primary value lies in enabling highly selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by research and development laboratories in the pharmaceutical, agrochemical, and advanced materials sectors for the asymmetric synthesis of novel compounds and intermediates.

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling: A key reagent for the stereoselective formation of carbon-carbon bonds, crucial for creating chiral active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and production of chiral drug candidates and complex organic molecules with defined stereochemistry.
• Agrochemical Development: Employed in the synthesis of novel, biologically active compounds with specific stereoisomers for crop protection.
• Advanced Materials Research: Facilitates the creation of chiral ligands, catalysts, and organic electronic materials with tailored properties.
• Academic & Process Chemistry: A vital tool for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	Bis[(-)Pinanediolato]Diboron
CAS No.	230299-05-5
Molecular Formula	C₂₀H₃₂B₂O₄
Molecular Weight	358.08 g/mol
Synonyms	(-)-Pinanediol Diboron; (R)-(-)-Pinanediol Diboron; Diboron Pinanediol Ester; (R)-5,5-Dimethyl-4-phenyl-1,3,2-dioxaborolane-2-yl)borane (related structure); B₂(Pin)₂; Chiral Diboron Reagent; Pinacolborane Dimer (chiral variant); 4,4,5,5-Tetramethyl-2-(pinan-2,3-diolato)-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Bis[(-)Pinanediolato]Diboron is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis to confirm identity, assay, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.