Description

5-(4-Methylphenyl)Nicotinaldehyde is a specialized aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a nicotinaldehyde core and a methylphenyl substituent, makes it a valuable precursor for constructing complex heterocyclic systems and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, due to its conjugated system.
• Chemical Research & Development: A versatile building block for academic and industrial R&D focused on heterocyclic chemistry and novel organic transformations.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	5-(4-Methylphenyl)Nicotinaldehyde
CAS No.	229008-16-6
Molecular Formula	C13H11NO
Molecular Weight	197.23 g/mol
Synonyms	5-(p-Tolyl)nicotinaldehyde; 5-(4-Methylphenyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 5-(4-methylphenyl)-; 5-(4-Methylphenyl)pyridine-3-carbaldehyde; 5-(p-Methylphenyl)nicotinaldehyde; 229008-16-6; Aldehyde, 5-(4-methylphenyl)-3-pyridyl
EINECS	Contact for details

Quality Control

Our 5-(4-Methylphenyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards where applicable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.