Description

(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(L)Tetrafluoroborate is a high-purity, chiral transition metal complex widely recognized as a highly efficient asymmetric hydrogenation catalyst. This compound is critical for achieving exceptional enantioselectivity and catalytic activity in the synthesis of fine chemicals and active pharmaceutical ingredients (APIs). It is an essential tool for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Key catalyst in the production of chiral drugs, including β-amino acids, unnatural amino acids, and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of high-value chiral building blocks and specialty chemicals for flavors, fragrances, and electronic materials.
• Academic & Industrial R&D: A benchmark catalyst for method development and exploring new asymmetric transformations in organic chemistry.
• Process Chemistry Optimization: Employed for scaling up enantioselective reactions from laboratory to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(L)Tetrafluoroborate
CAS No.	228121-39-9
Molecular Formula	C36H56BF4P2Rh
Molecular Weight	720.48 g/mol
Synonyms	(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (R,R)-Et-DuPhos Rh(COD)BF4; Rhodium(I) (1,2,5,6-η)-1,5-cyclooctadiene[(2R,5R)-2,5-diethylphospholano]benzene tetrafluoroborate; (R,R)-Et-DuPhos Rhodium Catalyst; DuPhos Rh(COD)BF4; Asymmetric Hydrogenation Catalyst Rh-Et-DuPhos; [Rh((R,R)-Et-DuPhos)(COD)]BF4
EINECS	Contact for details

Quality Control

Our (-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(L)Tetrafluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques, including NMR and HPLC, to confirm identity, purity, and enantiomeric excess of the ligand. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (argon or nitrogen) to maintain stability and catalytic activity. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red-brown crystalline or amorphous solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, toluene, THF; slightly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.