Description

2-Chloro-4-(m-Tolylamino)Pyrimidine-5-Carboxylic Acid is a high-purity pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which enables the construction of complex molecules for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create specialized pyrimidine libraries for screening.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Fundamental reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2-Chloro-4-(m-Tolylamino)Pyrimidine-5-Carboxylic Acid
CAS No.	227449-26-5
Molecular Formula	C12H10ClN3O2
Molecular Weight	263.68 g/mol
Synonyms	2-Chloro-4-[(3-methylphenyl)amino]pyrimidine-5-carboxylic acid; 4-[(3-Methylphenyl)amino]-2-chloropyrimidine-5-carboxylic acid; 2-Chloro-4-(3-methylanilino)pyrimidine-5-carboxylic acid; 2-Chloro-4-(m-toluidino)pyrimidine-5-carboxylic acid; 227449-26-5; 2-Chloro-4-(3-methylphenylamino)pyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(3-methylphenyl)amino]-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(m-Tolylamino)Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.