Description

4-(2-(1-Pyrrolidinyl)Ethoxy)Phenylboron is a specialized organoboron compound featuring a unique molecular scaffold that combines a phenylboron moiety with a pyrrolidine-ethoxy linker. This structure matters for its utility as a key synthetic intermediate and building block in advanced pharmaceutical and agrochemical research, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its boronic ester functionality for structural diversification.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials, such as those used in OLEDs or organic photovoltaics.
• Chemical Synthesis: A versatile reagent in palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura) to form biaryl and other carbon-carbon bonds.
• Ligand & Catalyst Development: The pyrrolidine nitrogen can act as a coordinating site, making it a candidate for developing novel ligands in asymmetric catalysis.
• Life Science Probes: Potential use in the development of biochemical probes and diagnostic agents due to its modifiable boron center.

Basic Information

Product Name	4-(2-(1-Pyrrolidinyl)Ethoxy)Phenylboron
CAS No.	226396-30-1
Molecular Formula	C12H18BNO2
Molecular Weight	219.09 g/mol
Synonyms	4-[2-(Pyrrolidin-1-yl)ethoxy]phenylboronic acid; [4-[2-(1-Pyrrolidinyl)ethoxy]phenyl]boronic acid; 4-(2-Pyrrolidin-1-ylethoxy)benzeneboronic acid; 4-(2-(Pyrrolidin-1-yl)ethoxy)benzeneboronic acid; B-[4-[2-(1-Pyrrolidinyl)ethoxy]phenyl]boronic acid; 226396-30-1; 4-(2-Pyrrolidinoethoxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(2-(1-Pyrrolidinyl)Ethoxy)Phenylboron is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container sealed and handle in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.