Description

1,2-Cyclohexanediol,3-Methylene-6-(1-Methylethyl)-,(1R,2R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral compound, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its unique bicyclic diol structure with an isopropyl substituent, which provides a rigid, functionalized scaffold for constructing complex molecules. This product is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials where precise stereochemistry is paramount. The compound, identified by CAS No. 223918-63-6, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding R&D and scale-up applications.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in antiviral, anti-inflammatory, or central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structural complexity can contribute to unique biological activity.
• Asymmetric Catalyst Ligand Precursor: The chiral diol framework can be modified to create novel ligands for asymmetric catalysis, enhancing enantioselectivity in critical bond-forming reactions.
• Fine Chemical and Specialty Material Production: Serves as a starting material for high-value flavors, fragrances, and advanced polymers requiring specific stereochemical configurations.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and the synthesis of complex natural product analogs.

Basic Information

Item	Details
Product Name	1,2-Cyclohexanediol,3-Methylene-6-(1-Methylethyl)-,(1R,2R,6R)-Rel-(9Ci)
CAS No.	223918-63-6
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(1R,2R,6R)-3-Methylene-6-(propan-2-yl)cyclohexane-1,2-diol; rel-(1R,2R,6R)-3-Methylene-6-(1-methylethyl)-1,2-cyclohexanediol; (-)-Isopulegol-1,2-diol derivative; Bicyclic terpene diol; 3-Isopropyl-6-methylene-1,2-cyclohexanediol (stereospecific); Chiral cyclohexanediol derivative; Terpene-based chiral diol.
EINECS	Contact for details

Quality Control

Every batch of 1,2-Cyclohexanediol,3-Methylene-6-(1-Methylethyl)-,(1R,2R,6R)-Rel-(9Ci) is produced and verified under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR spectroscopy, to ensure high chemical and enantiomeric purity critical for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.