Description

5,5-Dimethyl-2-(3-Methylphenyl)-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, valued for its role as a key synthetic intermediate in modern organic chemistry. Its primary importance lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules in a controlled manner. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for drug discovery, ligand synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators that require specific aryl-boron motifs.
• Material Science: Serves as a precursor for creating organic electronic materials, including polymers and small molecules for OLEDs and organic semiconductors.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the construction of complex organic architectures.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal complexes and catalysts used in asymmetric synthesis.
• Fine Chemical Production: Acts as an intermediate in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	5,5-Dimethyl-2-(3-Methylphenyl)-1,3,2-Dioxaborinane
CAS No.	223799-24-4
Molecular Formula	C13H19BO2
Molecular Weight	218.10 g/mol
Synonyms	3-Methylbenzeneboronic Acid, 5,5-Dimethyl-1,3,2-dioxaborinane Ester; (3-Methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 2-(3-Methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; m-Tolylboronic Acid Pinacol Ester (common name); 3-Methylphenylboronic Acid Pinacol Ester; 3-Methylbenzeneboronic Acid Pinanediol Ester (related); B-(3-Methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 5,5-Dimethyl-2-(3-Methylphenyl)-1,3,2-Dioxaborinane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant industry standards and can support development projects requiring specific analytical data or regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.