Description

5-Acetyl-2-Nitrobenzonitrile is a versatile and high-purity organic intermediate with the CAS registry number 223726-10-1. This compound is valued for its unique bifunctional structure, featuring both a nitrile and an acetyl group adjacent to a nitro substituent, which makes it a critical building block for complex chemical synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds and potential active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive nitro and cyano groups.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and organic pigments due to its aromatic nitro functionality.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced polymeric materials.
• Chemical Research & Development: A valuable building block for organic chemists in academia and industry for constructing complex molecular architectures.
• Cross-Coupling Reactions: Suitable for use in palladium-catalyzed reactions, such as Suzuki or Buchwald-Hartwig couplings, to create biaryl structures.

Basic Information

Product Name	5-Acetyl-2-Nitrobenzonitrile
CAS No.	223726-10-1
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	2-Nitro-5-acetylbenzonitrile; 1-(4-Cyano-3-nitrophenyl)ethanone; 5-Acetyl-2-nitrobenzenecarbonitrile; 4-Cyano-3-nitroacetophenone; 2-Nitro-5-acetylbenzenenitrile; Ethanone, 1-(4-cyano-3-nitrophenyl)-; 223726-10-1; 5-Acetyl-2-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.