Description

(R)-Methyl 5-Bromo-2-(1-Pivalamidoethyl)Benzoate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex, optically active molecules, enabling the development of targeted therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used in the construction of complex molecules where the (R)-configuration is essential for biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential drug candidates during clinical trial material preparation.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(R)-Methyl 5-Bromo-2-(1-Pivalamidoethyl)Benzoate
CAS No.	223595-13-9
Molecular Formula	C₁₅H₂₀BrNO₃
Molecular Weight	342.23 g/mol
Synonyms	Methyl (R)-5-bromo-2-(1-(pivalamido)ethyl)benzoate; (R)-5-Bromo-2-(1-pivalamidoethyl)benzoic acid methyl ester; Benzoic acid, 5-bromo-2-[1-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]-, methyl ester, (R)-; (R)-Methyl 5-bromo-2-(1-(2,2-dimethylpropanamido)ethyl)benzoate; (R)-MBPEB; Pivalamide derivative, (R)-isomer
EINECS	Contact for details

Quality Control

Our (R)-Methyl 5-Bromo-2-(1-Pivalamidoethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.