Description

4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-2-Carbaldehyde is a high-purity, multi-functional biphenyl derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogenated aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated biphenyl core.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational unit for creating specialized organic electronic materials and liquid crystal compounds.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for further functionalization into alcohols, acids, or amines.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and novel chemical entities.
• Material Science: Used in the development of polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-2-Carbaldehyde
CAS No.	223575-82-4
Molecular Formula	C₁₃H₈ClFO
Molecular Weight	234.65 g/mol
Synonyms	2-Formyl-4'-chloro-3'-fluorobiphenyl; (4'-Chloro-3'-fluorobiphenyl-2-yl)methanal; 4'-Chloro-3'-fluoro-2-biphenylcarboxaldehyde; 2-Biphenylcarboxaldehyde, 4'-chloro-3'-fluoro-; 4-Chloro-3-fluoro[1,1'-biphenyl]-2-carbaldehyde; 4'-Chloro-3'-fluorobiphenyl-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.